The ANU reporter has an intriguing story on work being done by their Research School of Chemistry and Dr Mal Mcleod on figuring out how to test greyhounds for drugs.
- Yet despite the increasing success of catching sports drug cheats of the human and equine varieties, the same testing methods do not apply to greyhounds. All this rests on the analysis of metabolites – the products of chemical reactions within an organism when it attempts to break down complex molecules and eliminate them from the body.
The human metabolites of stanozolol do not match the major metabolite obtained when the same drug is administered to greyhounds.
Drugs metabolise differently in humans to greyhounds. Until now nobody performed the research on dogs to work out why.
As part of their experiments, McLeod’s team made a number of new compounds. One of these was called 6 alpha-hydroxystanozolol, which was found to match the greyhound metabolite. This discovery has led to numerous positive swabs for stanozolol doping in greyhounds around the country.
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